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As previously mentioned, Testosterone Enanthate is simply Testosterone with the Enanthate ester bound to the Testosterone chemical structure. Specifically ‘Enanthate’ is Enanthoic acid, but once bound to Testosterone it is properly referred to in chemistry as an ester bond (or ester linkage). Enanthoic acid is bonded to the 17-beta hydroxyl group on the Testosterone structure. Esterified anabolic steroids are more fat soluble, and release slowly from the injection site – however, this is not the main reason as to why esters extend the release rate of the anabolic steroid. The primary reason for the augmentation of its half-life and release rate is because once Testosterone Enanthate enters the bloodstream, enzymes work to break the bond between the ester and the hormone, which takes a varying amount of time. The end result is that the ester is removed from the hormone by enzymes, and what is left is pure Testosterone that is free to do its work in the body. This process of enzymes cleaving off the ester from the Testosterone molecule is what is responsible for the slower release rates. Testosterone alone with no ester bonded to it possesses a half-life of approximately 2 – 4 hours. When the Enanthate ester is attached to it, creating Testosterone Enanthate, the half-life of Testosterone is now extended to 10 days, providing a slower release and activity of the hormone.
Testosterone Enanthate is an anabolic steroid with a very moderate side effect profile. When considering its benefits in terms of potential gains and strength versus its side effect potential and profile, it can be considered a very reasonable anabolic steroid in this regard. Testosterone Enanthate’s side effect distribution is generally pretty varied, but what one must understand is that Testosterone Enanthate being a Testosterone compound, is the body’s most natural anabolic hormone. After all, Testosterone is what the body endogenously manufactures naturally and it is therefore what the body is most accustomed to first and foremost. As with any side effects of any sort, individual body reaction, sensitivity, and genetics play a large factor in whether or not an individual may experience more or less of a certain side effect (or experience none at all).
Testosterone Enanthate side effects include that of estrogenic side effects, which are the most prominent side effects that users and potential users are most concerned about. This results from the fact that Testosterone is a moderately aromatizable anabolic steroid (meaning Testosterone undergoes conversion into Estrogen at a moderate rate in the body), and this is of course proportional to the dose of Testosterone Enanthate used as well. The greater the dosage, the greater the degree of aromatization into Estrogen. The resultant side effects of Estrogen conversion can include: water retention and bloating, increases in blood pressure (resultant from water retention), increased fat gain/retention, and potential development of gynecomastia.
Androgenic side effects are also a potential experience with the use of Testosterone Enanthate. Being that Testosterone is an androgen in and of itself, it does interact with androgen receptors throughout the body and will exhibit androgenic side effects. However, the real bulk of the androgenic side effects are the result of Testosterone’s reduction into a much stronger androgen, Dihydrotestosterone (DHT). This occurs in a few key tissues in the body as Testosterone passes through them, such as the scalp, prostate, and skin. Androgenic side effects can include: increased oily skin (sebum secretion), increased acne formation (linked to sebum secretion), bodily and facial hair growth, and the increased risk of experiencing male pattern baldness (MPB) if the individual possesses the genetic predisposition for it. Studies have not found Testosterone Enanthate to be liver toxic (hepatotoxic) at any dosage, even at extreme dosages administered orally. There is no risk for liver issues with Testosterone Enanthate.
Testosterone Enanthate cycles are usually that of a bulking or mass gaining nature, though it can also be utilized in a very specific manner in cutting or fat loss cycles. For mass gaining or bulking, Testosterone Enanthate is usually employed in a higher dosage (usually a minimum of 500mg per week), and because it is an anabolic steroid with a long ester affixed to it, it will exhibit a longer half-life of around 7 – 10 days, and therefore Testosterone Enanthate cycles are usually run for periods of 10 – 12 weeks or longer.
In both bulking and cutting cycles, Testosterone Enanthate is commonly stacked with other compounds of a nature that will facilitate the user’s end goal (bulking, mass gaining, or fat loss). For example, Testosterone Enanthate cycles for the purpose of bulking usually include the use of Nandrolone Decanoate and/or Methandrostenolone, where Methandrostenolone is usually run for the first 6 weeks as a kick-starting compound.
In the event that Testosterone Enanthate cycles are cutting or fat loss cycles, Testosterone Enanthate is usually run at a very low TRT (Testosterone Replacement Therapy) dosage of around 100mg per week whilst other compounds more preferable for cutting and fat loss are emphasized during the cycle. The use of Testosterone Enanthate at this dosage is merely to maintain normal bodily function rather than to emphasize gains and performance enhancement.
Medically, Testosterone Enanthate is usually utilized at a prescription dosage of around 250mg administered once every 2 – 4 weeks, depending on the discretion of the physician and the patient’s progress in his TRT therapy.
For the purpose of bodybuilding and performance and physique enhancement, Testosterone Enanthate is usually dosed at around 300 – 500mg per week as a beginner dosage. Intermediate Testosterone Enanthate dosages can run from 500 – 750mg per week, and advanced users are known to utilize upwards of 1,000mg or more per week of Testosterone Enanthate.
Because of its half-life of 7 – 10 days, it is recommended that Testosterone Enanthate’s administration occur at a minimum of once per week, but ideally for optimal performance and results (and minimization of unwanted side effects due to spiking blood plasma levels), it should be administered twice per week with the weekly dosage split evenly between administrations. For example, a 500mg per week dosage of Testosterone Enanthate should be administered as 250mg on Monday and 250mg on Thursday every week.
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